VITAMIN B12 VEGGUNN VEGGUNN FLASH SUBLINGUAL TABLETS
At Veggunn, we have designed our product based on knowledge of the behavior of vitamin B12, based on scientific foundations.
Briefly, we present what the scientific evidence reveals. The safest and most effective form of vitamin B12 is in the chemical form of cyanocobalamin. Regarding the dose, professionals recommend as the preferred dose to take, in a healthy adult, 2000 mcg a week. It can be taken in a single dose, or divided into 2 doses of 1000 mcg each. The recommended form of administration is sublingual, since under the tongue we have many capillaries, which allow it to directly access the bloodstream, avoiding the effect of the first step and ensuring that the absorbed dose is accurate. In this way, the bioavailability of the vitamin is maximum, since it does not require subsequent metabolizations by our body.
Top technology to improve absorption
Why have we concluded that the flash tablet is the optimal way to absorb vitamin B12? At Veggunn we link cutting-edge technology and scientific evidence regarding vitamin B12.
The sublingual mucosa offers a small absorption surface. This mucosa is exclusively permeable to the passage of non-ionic, fat-soluble substances with high molecular weight. To do this, we define the formulation of our tablets according to the physiological properties of the sublingual mucosa. Thus, we achieve a synergy between the Veggunn formulation, the physiology of the sublingual tissues and the properties of vitamin B12 per se, which contributes to its passage into the bloodstream, achieving the objective of the product.
In the application of cutting-edge technology, the characteristics of vitamin B12 have been taken into account to obtain its optimization according to all parameters:
- Dosage
- Therapeutic efficacy
- Stability over time
In recent years there has been a great advance in the development of new modified release presentations, also known as controlled release, which are presented as products that provide better dosage guidelines, a better kinetic profile and a reduction in adverse effects. Veggunn has joined the forefront, carrying out a technological investment, made available to clinical relevance.
In fact, they are defined as presentations in which the rate and the site of release of the active substance is different from that of the conventional release form, administered by the same route.
The advantages of sublingual bioavailability
FLASH Veggunn sublingual tablets are accelerated release forms, that is, solid forms that dissolve almost instantly in the oral cavity without the need for fluid administration. They are rapidly disintegrating tablets, with adequate hydroliposolubility, in contact with the sublingual moist environment.
Thus, they allow to increase the bioavailability of vitamin B12 sublingual tablets by reducing the effect of the first pass due to its sublingual absorption through the oral mucosa. In this way, they allow a plasma concentration profile to be achieved that guarantees the persistence of the vitamin’s action.
Also, the rate of absorption is higher than the oral route. For this, various factors have to be taken into account:
- Solubility in salivary secretions
- Synergy with the pH of saliva
- Reduced binding to the oral mucosa
- Oral epithelium thickness: the thickness of the sublingual epithelium is 100-200 µm less than that of the oral epithelium. Therefore, the absorption of vitamin B12 is faster since the epithelium is thinner and also because it is immersed in a smaller volume of saliva
- Oil / water partition coefficient suitable for absorption through the mucosa
- Low compression force: avoid hardness and disintegration difficulty
If you are interested in other sublingual forms of vitamin B12, here you can find our vitamin B12 Family, which due to its characteristics is especially suitable for the whole family and for those people who ponder the fact that what they take does not contain preservatives or other types of additives.
